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Roles of miR-137 in muscular dystrophy and muscular dystrophy-related phenotypes in drosophila melanogaster
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Erscheint auch als: | Chhetri, Shruti, 1986 - , Roles of miR-137 in muscular dystrophy and muscular dystrophy-related phenotypes in drosophila melanogaster, Göttingen, 2019, 131 Seiten |
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Personen und Körperschaften: | , , , |
Titel: | Roles of miR-137 in muscular dystrophy and muscular dystrophy-related phenotypes in drosophila melanogaster/ submitted by Shruti Chhetri ; Reviewer: Prof. Dr. Halyna Shcherbata, 2. Reviewer: Prof. Dr. Stefan Bonn Prof. Dr. Jörg Großhans |
Hochschulschriftenvermerk: | Dissertation, Georg-August-Universität Göttingen, 2019 |
veröffentlicht: |
Göttingen:
2019
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Umfang: | 1 Online-Ressource; Illustrationen, Diagramme |
Zusammenfassung: | Muscular dystrophies (MDs) are a group of diseases that cause muscular and neurological disorders in human patients. They are associated with a multi-component complex called the Dystrophin Glycoprotein Complex (DGC). The DGC connects the extracellular matrix to the cytoskeleton and is well-conserved in animals. Perturbation of this complex is associated with various kinds of MDs, leading to a diverse range of muscle and nervous system abnormalities. Dystroglycan (Dg) is a central DGC component, mutations of which are associated with a heterogeneous group of MDs also known as dystroglycanop... |
Format: | E-Book Hochschulschrift |
Quelle: |
Verbunddaten SWB Lizenzfreie Online-Ressourcen |
Sprache: | Englisch |