Eintrag weiter verarbeiten
Anthraquinones in Rheum palmatum and Rumex dentatus(Polygonaceae), and phorbol esters in Jatropha curcas(Euphorbiaceae) with molluscicidal activity against the schistosom...
Gespeichert in:
Personen und Körperschaften: | , , , , , , |
---|---|
Titel: |
Anthraquinones in Rheum palmatum and Rumex dentatus(Polygonaceae), and phorbol esters in Jatropha curcas(Euphorbiaceae) with molluscicidal activity against the schistosome vector snails Oncomelania,Biomphalaria, and Bulinus |
In: | Tropical Medicine & International Health, 2, 1997, 2, S. 179-188 |
veröffentlicht: |
Wiley
|
Umfang: | 179-188 |
ISSN: |
1360-2276 1365-3156 |
DOI: | 10.1046/j.1365-3156.1997.d01-242.x |
Zusammenfassung: | <jats:p>Hot water extracts of <jats:italic>Rheum palmatum</jats:italic> and <jats:italic>Rheum dentatus</jats:italic> (from China) showed molluscicidal activity against the snails <jats:italic>Oncomelania hupensis, Biomphalaria glabrata</jats:italic> and <jats:italic>Bulinus globosus</jats:italic> which are vectors of <jats:italic>Schistosoma japonicum</jats:italic><jats:italic>S. mansoni</jats:italic> and <jats:italic>S. haematobium</jats:italic> respectively. Activity was correlated with anthraquinones which were identified by HPLC: rhein and chrysophanol‐anthron were most active (>50% dead snails after 2 days in a 0.03% solution). Molluscicidal activity was intermediate with Rheum‐emodin and physcion and was not detectable with cinnamic acid or Aloe‐emodin. The snail <jats:italic>O. hupensis</jats:italic> tended to be more sensitive for several compounds than <jats:italic>B. glabrata</jats:italic> Extracts of <jats:italic>Jatropha curcas</jats:italic> seeds (from Mali) showed molluscicidal activity against both <jats:italic>B. glabrata</jats:italic> and <jats:italic>O. hupensis</jats:italic> the latter being the more sensitive snail. The activity was associated with phorbol esters extracted from <jats:italic>Jatropha</jats:italic> oil. Of the pure phorbol esters tested, 4β‐phorbol‐13‐decanoate killed both snail species at a concentration of 0.001% (10 p.p.m). As <jats:italic>Jatropha </jats:italic>is locally grown in Mali for other purposes, it might potentially be exploited for schistosomiasis control.</jats:p> |
Format: | E-Article |
Quelle: | Wiley (CrossRef) |
Sprache: | Englisch |