Temporal trends in adoption and outcomes of transcatheter aortic valve implantation: a SwissTAVI Registry analysis

Bibliographic Details
Authors and Corporations: Stortecky, Stefan, Franzone, Anna, Heg, Dik, Tueller, David, Noble, Stephane, Pilgrim, Thomas, Jeger, Raban, Toggweiler, Stefan, Ferrari, Enrico, Nietlispach, Fabian, Taramasso, Maurizio, Maisano, Francesco, Grünenfelder, Jürg, Muller, Olivier, Huber, Christoph, Roffi, Marco, Carrel, Thierry, Wenaweser, Peter, Windecker, Stephan
Title: Temporal trends in adoption and outcomes of transcatheter aortic valve implantation: a SwissTAVI Registry analysis
In: European Heart Journal - Quality of Care and Clinical Outcomes, 5, 2019, 3, p. 242-251
Oxford University Press (OUP)
Physical Description:242-251
ISSN/ISBN: 2058-5225
Summary:<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Aims</jats:title> <jats:p>To describe temporal trends in adoption and performance of transcatheter aortic valve implantation (TAVI) in Switzerland over a period of 5 years.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods and results</jats:title> <jats:p>Between 2011 and 2015, a total of 3493 patients were consecutively included in the SwissTAVI Registry (NCT01368250) and analysed for the purpose of this study. The primary outcome measure was all-cause mortality at 1 year after TAVI. Over the 5-year period, a six-fold increase in the number of procedures was observed, whereas the baseline surgical risk estimated by the Society of Thoracic Surgeon (STS) score declined (from 6.8 ± 4.4% to 4.6 ± 3.6, P &lt; 0.001). Overall, 1-year mortality amounted to 12.8%; mortality was highest in the first annual cohorts (14.6%, 14.8%, and 15.9% in 2011, 2012, and 2013, respectively) and decreased to 13.4% in 2014 and 9.7% in 2015. While rates of cerebrovascular events, peri-procedural myocardial infarction, moderate/severe paravalvular regurgitation, and Stage 3 acute kidney injury did not significantly change over time, a significant reduction in life threatening or major bleeding was noted at 30-day follow-up during the latest compared with earlier years of recruitment.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusion</jats:title> <jats:p>This long-term recruitment analysis of a national TAVI registry showed rapid adoption paralleled by a progressive decrease of patients’ baseline risk profile. Early and late survival significantly improved over time as did the rate of life threatening or major bleeding.</jats:p> </jats:sec>
Type of Resource:E-Article
Source:Oxford University Press (OUP) (CrossRef)
Language: English