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Induction of resting B cells to DNA synthesis by soluble monoclonal anti‐immunoglobulin
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Personen und Körperschaften: | , , |
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Titel: |
Induction of resting B cells to DNA synthesis by soluble monoclonal anti‐immunoglobulin |
In: | European Journal of Immunology, 14, 1984, 8, S. 753-757 |
veröffentlicht: |
Wiley
|
Umfang: | 753-757 |
ISSN: |
1521-4141 0014-2980 |
DOI: | 10.1002/eji.1830140816 |
Zusammenfassung: | <jats:title>Abstract</jats:title><jats:p>A novel monoclonal anti‐immunoglobulin is described which in soluble form is comparable to lipopolysaccharide in its ability to induce DNA synthesis in populations of resting B cells. It inhibits lipopolysaccharide‐induced B cell maturation to immuno‐globulin secretion while not suppressing mitogen‐induced proliferative responses. B cells from C3H/HeJ mice are stimulated as well as those from C3H/Tif mice demonstrating that the induction capacity of this monoclonal antibody does not involve functional lipopolysaccharide receptor molecules.</jats:p> |
Format: | E-Article |
Quelle: | Wiley (CrossRef) |
Sprache: | Englisch |