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Postoperative Bleeding Risk for Oral Surgery under Continued Clopidogrel Antiplatelet Therapy
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Personen und Körperschaften: | , , , , , , , , , , , |
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Titel: |
Postoperative Bleeding Risk for Oral Surgery under Continued Clopidogrel Antiplatelet Therapy |
In: | BioMed Research International, 2015, 2015, S. 1-4 |
veröffentlicht: |
Hindawi Limited
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Umfang: | 1-4 |
ISSN: |
2314-6141 2314-6133 |
DOI: | 10.1155/2015/823651 |
Zusammenfassung: | <jats:p><jats:italic>Object.</jats:italic>To determine the incidence of postoperative bleeding for oral osteotomy carried out under continued monoantiplatelet therapy with clopidogrel and dual therapy with clopidogrel/aspirin.<jats:italic>Design.</jats:italic>Retrospective single center observatory study of two study groups and a control group.<jats:italic>Methods.</jats:italic>A total of 64 and 60 oral osteotomy procedures carried out under continued monoclopidogrel therapy and dual clopidogrel/aspirin therapy, respectively, were followed for two weeks for postoperative bleeding. Another 281 similar procedures were also followed as a control group. All oral osteotomy procedures were carried out on an outpatient basis.<jats:italic>Results.</jats:italic>We observed postoperative bleeding in 2/281 (0.7%) cases in the control group, in 1/64 (1.6%) cases in the clopidogrel group, and in 2/60 (3.3%) cases in the dual clopidogrel/aspirin group. The corresponding 95% confidence intervals are 0–1.7%, 0–4.7%, and 0–7.8%, respectively, and the incidences did not differ significantly among the three groups (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>P</mml:mi><mml:mo>></mml:mo><mml:mn>0.09</mml:mn></mml:math>). Postoperative hemorrhage was treated successfully in all cases with local measures. No changes of antiplatelet medication, transfusion, nor hospitalisation were necessary. No major cardiovascular events were recorded.<jats:italic>Conclusions.</jats:italic>Our results indicate that minor oral surgery can be performed safely under continued monoantiplatelet medication with clopidogrel or dual antiplatelet medication with clopidogrel/aspirin.</jats:p> |
Format: | E-Article |
Quelle: | Hindawi Limited (CrossRef) |
Sprache: | Englisch |