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Wiring taste receptor cells to the central gustatory system
Gespeichert in:
Personen und Körperschaften: | , |
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Titel: |
Wiring taste receptor cells to the central gustatory system |
In: | Oral Diseases, 24, 2018, 8, S. 1388-1389 |
veröffentlicht: |
Wiley
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Umfang: | 1388-1389 |
ISSN: |
1354-523X 1601-0825 |
DOI: | 10.1111/odi.12833 |
Zusammenfassung: | <jats:p>Taste receptor cells in the tongue are epithelial in nature and turnover frequently. Taste receptor cell‐associated neurons carrying bitter, sweet, or sour signals never turnover and are hardwired to specific gustatory centers in the brain. How can <jats:italic>ever‐changing</jats:italic> bitter or sweet receptors find <jats:italic>never‐changing</jats:italic> neurons that must match the specificity of the signal? This article reviews a recent paper published in Nature (Lee, MacPherson, Parada, Zuker, & Ryba, <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#odi12833-bib-0001" />, 548:330‐333) that identified two molecules belonging to the <jats:italic>semaphorin</jats:italic> axon guidance family of molecules (<jats:styled-content style="fixed-case">SEMA</jats:styled-content>3A and <jats:styled-content style="fixed-case">SEMA</jats:styled-content>7A) that help maintain the “labeled line principle” between peripheral bitter or sweet receptors and their respective central projection area in the gustatory center.</jats:p> |
Format: | E-Article |
Quelle: | Wiley (CrossRef) |
Sprache: | Englisch |