Impact of restriction of third generation cephalosporins on the burden of third generation cephalosporin resistant K. pneumoniae and E. coli in an ICU

Bibliographic Details
Authors and Corporations: Meyer, Elisabeth
Title: Impact of restriction of third generation cephalosporins on the burden of third generation cephalosporin resistant K. pneumoniae and E. coli in an ICU
In: Intensive Care Medicine, 35, 2009, 5, p. 862-870
published:
Springer-Verlag
Physical Description:862-870
ISSN/ISBN: 0342-4642
1432-1238
EISSN:1432-1238
Summary:Objective<br/>Reducing 3GCs does not necessarily impact positively on the resistance situation in the ICU setting. Likewise, replacing piperacillin with β-lactamase inhibitor might provide a selection pressure on 3GC resistant <Emphasis Type="Italic">E. coli</Emphasis> and <Emphasis Type="Italic">K. pneumoniae.</Emphasis> To improve resistance, it might not be sufficient to restrict interventions to a risk area.<br/>Design<br/>Reducing 3GCs does not necessarily impact positively on the resistance situation in the ICU setting. Likewise, replacing piperacillin with β-lactamase inhibitor might provide a selection pressure on 3GC resistant <Emphasis Type="Italic">E. coli</Emphasis> and <Emphasis Type="Italic">K. pneumoniae.</Emphasis> To improve resistance, it might not be sufficient to restrict interventions to a risk area.<br/>Setting<br/>Reducing 3GCs does not necessarily impact positively on the resistance situation in the ICU setting. Likewise, replacing piperacillin with β-lactamase inhibitor might provide a selection pressure on 3GC resistant <Emphasis Type="Italic">E. coli</Emphasis> and <Emphasis Type="Italic">K. pneumoniae.</Emphasis> To improve resistance, it might not be sufficient to restrict interventions to a risk area.<br/>Intervention<br/>Reducing 3GCs does not necessarily impact positively on the resistance situation in the ICU setting. Likewise, replacing piperacillin with β-lactamase inhibitor might provide a selection pressure on 3GC resistant <Emphasis Type="Italic">E. coli</Emphasis> and <Emphasis Type="Italic">K. pneumoniae.</Emphasis> To improve resistance, it might not be sufficient to restrict interventions to a risk area.<br/>Results<br/>Reducing 3GCs does not necessarily impact positively on the resistance situation in the ICU setting. Likewise, replacing piperacillin with β-lactamase inhibitor might provide a selection pressure on 3GC resistant <Emphasis Type="Italic">E. coli</Emphasis> and <Emphasis Type="Italic">K. pneumoniae.</Emphasis> To improve resistance, it might not be sufficient to restrict interventions to a risk area.<br/>Conclusion<br/>Reducing 3GCs does not necessarily impact positively on the resistance situation in the ICU setting. Likewise, replacing piperacillin with β-lactamase inhibitor might provide a selection pressure on 3GC resistant <Emphasis Type="Italic">E. coli</Emphasis> and <Emphasis Type="Italic">K. pneumoniae.</Emphasis> To improve resistance, it might not be sufficient to restrict interventions to a risk area.<br/>
Type of Resource:E-Article
Source:Springer Journals
sid-105-col-springerjournals
Language: English